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HMGB1 promotes Ox-LDL-induced endothelial cell damage by inhibiting PI3K/Akt signaling pathway

BACKGROUND: Atherosclerosis is the pathological basis of cardio-cerebrovascular diseases. Oxidized low-density lipoprotein (ox-LDL) is an important risk factor for atherosclerosis. Ox-LDL leads to endothelial cell (EC) damage and dysfunction through various processes and promotes the occurrence and...

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Detalles Bibliográficos
Autores principales: Huo, Xin, Su, Boyou, Qin, Guoti, Zhao, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768960/
https://www.ncbi.nlm.nih.gov/pubmed/36544080
http://dx.doi.org/10.1186/s12872-022-03003-y