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Installation of electrophiles onto the C-terminus of recombinant ubiquitin and ubiquitin-like proteins
Ubiquitin and related ubiquitin-like proteins (Ubls) influence a variety of cellular pathways including protein degradation and response to viral infections. The chemical interrogation of these complex enzymatic cascades relies on the use of tailored activity-based probes (ABPs). Herein, we report t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769091/ https://www.ncbi.nlm.nih.gov/pubmed/36605735 http://dx.doi.org/10.1039/d2sc04279g |