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Installation of electrophiles onto the C-terminus of recombinant ubiquitin and ubiquitin-like proteins

Ubiquitin and related ubiquitin-like proteins (Ubls) influence a variety of cellular pathways including protein degradation and response to viral infections. The chemical interrogation of these complex enzymatic cascades relies on the use of tailored activity-based probes (ABPs). Herein, we report t...

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Detalles Bibliográficos
Autores principales:	Farnung, Jakob, Tolmachova, Kateryna A., Bode, Jeffrey W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769091/ https://www.ncbi.nlm.nih.gov/pubmed/36605735 http://dx.doi.org/10.1039/d2sc04279g

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