Cobalt-electrocatalytic C–H hydroxyalkylation of N-heteroarenes with trifluoromethyl ketones

Trifluoromethyl carbinols and N-heteroarenes are both prevalent in bioactive molecules. However, access to high-value pharmacophores combining these two functional groups still remains a challenge. Herein, we report an electro-chemical redox-neutral coupling for the synthesis of N-heteroaryl trifluo...

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Detalles Bibliográficos
Autores principales: He, Tianyu, Liang, Chaoqiang, Huang, Shenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769098/
https://www.ncbi.nlm.nih.gov/pubmed/36605737
http://dx.doi.org/10.1039/d2sc05198b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769098/
https://www.ncbi.nlm.nih.gov/pubmed/36605737
http://dx.doi.org/10.1039/d2sc05198b

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