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Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron–sulfur cluster assembly

Iron–sulfur (Fe–S) clusters are cofactors essential for life. Though the proteins that function in the assembly of Fe–S clusters are well known, details of the molecular mechanism are less well established. The Isc (iron–sulfur cluster) biogenesis apparatus is widespread in bacteria and is the close...

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Detalles Bibliográficos
Autores principales: Bennett, Sophie P., Crack, Jason C., Puglisi, Rita, Pastore, Annalisa, Le Brun, Nick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769115/
https://www.ncbi.nlm.nih.gov/pubmed/36605734
http://dx.doi.org/10.1039/d2sc04169c