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Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp.

BACKGROUND: Scorpion neurotoxins such as those that modify the mammalian voltage-gated sodium ion channels (Nav) are the main responsible for scorpion envenomation. Their neutralization is crucial in the production of antivenoms against scorpion stings. METHODS: In the present study, two in silico d...

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Detalles Bibliográficos
Autores principales: Cardoso-Arenas, Samuel, Clement, Herlinda, Arenas, Iván, Olvera, Felipe, Zamudio, Fernando, Caliskan, Figen, Corrales-García, Ligia Luz, Corzo, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769139/
https://www.ncbi.nlm.nih.gov/pubmed/36578820
http://dx.doi.org/10.1590/1678-9199-JVATITD-2022-0026