Cargando…

Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection

Broadly neutralizing antibodies (bNAbs) for HIV-1 prevention or cure strategies must inhibit transmitted/founder and reservoir viruses. Establishing sensitivity of circulating viruses to bNAbs and genetic patterns affecting neutralization variability may guide rational bNAbs selection for clinical d...

Descripción completa

Detalles Bibliográficos
Autores principales: Mandizvo, Tawanda, Gumede, Nombali, Ndlovu, Bongiwe, Ndlovu, Siphiwe, Mann, Jaclyn K., Chopera, Denis R., Singh, Lanish, Dong, Krista L., Walker, Bruce D., Ndhlovu, Zaza M., Lavine, Christy L., Seaman, Michael S., Gounder, Kamini, Ndung’u, Thumbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769376/
https://www.ncbi.nlm.nih.gov/pubmed/36453881
http://dx.doi.org/10.1128/jvi.01270-22