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Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties

Leishmaniasis, a category I neglected tropical disease, is a group of diseases caused by the protozoan parasite Leishmania species with a wide range of clinical manifestations. Current treatment options can be highly toxic and expensive, with drug relapse and the emergence of resistance. Bacteriocin...

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Detalles Bibliográficos
Autores principales: Corman, Hannah N., Ross, Jessica N., Fields, Francisco R., Shoue, Douglas A., McDowell, Mary Ann, Lee, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769502/
https://www.ncbi.nlm.nih.gov/pubmed/36342284
http://dx.doi.org/10.1128/spectrum.02658-22