Interruption of Capsular Polysaccharide Biosynthesis Gene wbaZ by Insertion Sequence IS903B Mediates Resistance to a Lytic Phage against ST11 K64 Carbapenem-Resistant Klebsiella pneumoniae

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major challenge for clinical management worldwide with limited antimicrobial options. Phages are considered an alternative option. Here, we isolated and identified a phage able to lyse ST11-K64 CRKP, the major type in China. This phage has a nar...

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Detalles Bibliográficos
Autores principales: Yin, Xin, Fang, Qingqing, Zong, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769513/
https://www.ncbi.nlm.nih.gov/pubmed/36377881
http://dx.doi.org/10.1128/msphere.00518-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769513/
https://www.ncbi.nlm.nih.gov/pubmed/36377881
http://dx.doi.org/10.1128/msphere.00518-22

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