Cargando…

Interruption of Capsular Polysaccharide Biosynthesis Gene wbaZ by Insertion Sequence IS903B Mediates Resistance to a Lytic Phage against ST11 K64 Carbapenem-Resistant Klebsiella pneumoniae

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major challenge for clinical management worldwide with limited antimicrobial options. Phages are considered an alternative option. Here, we isolated and identified a phage able to lyse ST11-K64 CRKP, the major type in China. This phage has a nar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Xin, Fang, Qingqing, Zong, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769513/ https://www.ncbi.nlm.nih.gov/pubmed/36377881 http://dx.doi.org/10.1128/msphere.00518-22

Ejemplares similares

Lytic Phages against ST11 K47 Carbapenem-Resistant Klebsiella pneumoniae and the Corresponding Phage Resistance Mechanisms
por: Fang, Qingqing, et al.
Publicado: (2022)

Worldwide transmission of ST11-KL64 carbapenem-resistant Klebsiella pneumoniae: an analysis of publicly available genomes
por: Wang, Junna, et al.
Publicado: (2023)

Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice
por: Fang, Qingqing, et al.
Publicado: (2022)

Multicenter Study of Colistin Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae Strains in China
por: Weng, Yuesong, et al.
Publicado: (2023)

Identification of a newly isolated lytic bacteriophage against K24 capsular type, carbapenem resistant Klebsiella pneumoniae isolates
por: Horváth, Marianna, et al.
Publicado: (2020)

Carbapenem-Resistant Klebsiella pneumoniae Exhibiting Clinically Undetected Colistin Heteroresistance Leads to Treatment Failure in a Murine Model of Infection
por: Band, Victor I., et al.
Publicado: (2018)

A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible Klebsiella pneumoniae Strain Harboring bla(KPC-14) Isolated in New York City
por: Niu, Siqiang, et al.
Publicado: (2020)

The Mutation in wbaP cps Gene Cluster Selected by Phage-Borne Depolymerase Abolishes Capsule Production and Diminishes the Virulence of Klebsiella pneumoniae
por: Kaszowska, Marta, et al.
Publicado: (2021)

Molecular Characterization of the Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Strain K1-ST23, Collected in Chile during the COVID-19 Pandemic
por: Morales-León, Felipe, et al.
Publicado: (2023)

Emergence of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Coharboring a bla(NDM-1)-Carrying Virulent Plasmid and a bla(KPC-2)-Carrying Plasmid in an Egyptian Hospital
por: Ahmed, Mohamed Abd El-Gawad El-Sayed, et al.
Publicado: (2021)

Isolation and Characterization of Novel Lytic Bacteriophages Infecting Epidemic Carbapenem-Resistant Klebsiella pneumoniae Strains
por: Li, Min, et al.
Publicado: (2020)

Enhanced Carbapenem Resistance through Multimerization of Plasmids Carrying Carbapenemase Genes
por: Abe, Ryuichiro, et al.
Publicado: (2021)

Isolation and characterization of lytic phage TUN1 specific for Klebsiella pneumoniae K64 clinical isolates from Tunisia
por: Eckstein, Simone, et al.
Publicado: (2021)

Transmission Dynamics of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 Strains Carrying Capsular Loci KL64 and rmpA/rmpA2 Genes
por: Kong, Yingying, et al.
Publicado: (2021)

Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant Enterobacterales in the United States
por: Band, Victor I., et al.
Publicado: (2021)

Role of Chromosome- and/or Plasmid-Located bla(NDM) on the Carbapenem Resistance and the Gene Stability in Escherichia coli
por: Sakamoto, Noriko, et al.
Publicado: (2022)

Clinical characteristics and risk factors associated with secondary bloodstream infection in patients with intensive care unit-acquired pneumonia due to carbapenem-resistant Klebsiella pneumoniae
por: Zhu, Xin-Yun, et al.
Publicado: (2021)

An Alliance of Carbapenem-Resistant Klebsiella pneumoniae with Precise Capsular Serotypes and Clinical Determinants: A Disquietude in Hospital Setting
por: Soltani, Elghar, et al.
Publicado: (2022)

KDP 903
por: KEK. Tsukuba
Publicado: (1992)

Genomic Analysis of a Pan-Resistant Isolate of Klebsiella pneumoniae, United States 2016
por: de Man, Tom J. B., et al.
Publicado: (2018)

Presence of Mobile Tigecycline Resistance Gene tet(X4) in Clinical Klebsiella pneumoniae
por: Zhai, Weishuai, et al.
Publicado: (2022)

Two New Lytic Bacteriophages of the Myoviridae Family Against Carbapenem-Resistant Acinetobacter baumannii
por: Zhou, Weilong, et al.
Publicado: (2018)

Direct Detection of Carbapenem-Resistant Organisms from Environmental Samples Using the GeneXpert Molecular Diagnostic System
por: Perry, K. A., et al.
Publicado: (2018)

Pairing Colicins B and E5 with Bdellovibrio bacteriovorus To Eradicate Carbapenem- and Colistin-Resistant Strains of Escherichia coli
por: Upatissa, Sumudu, et al.
Publicado: (2023)

Klebsiella grimontii, a New Species Acquired Carbapenem Resistance
por: Liu, Lu, et al.
Publicado: (2018)

644. How Antibody Isotype Affects Anti-Capsular Antibody Protection Against Carbapenem-Resistant Klebsiella pneumoniae Infection
por: Motley, Michael, et al.
Publicado: (2018)

In Vitro Evolution of Cefiderocol Resistance in an NDM-Producing Klebsiella pneumoniae Due to Functional Loss of CirA
por: McElheny, Christi L., et al.
Publicado: (2021)

Characterization of Amino Acid Substitution W20S in MgrB Involved in Polymyxin Resistance in Klebsiella pneumoniae
por: Roch, Mélanie, et al.
Publicado: (2022)

Characterization of Klebsiella pneumoniae ST11 Isolates and Their Interactions with Lytic Phages
por: Tan, Demeng, et al.
Publicado: (2019)

Recombination Drives Evolution of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 KL47 to KL64 in China
por: Chen, Tao, et al.
Publicado: (2023)

Genetic Characteristics and Microbiological Profile of Hypermucoviscous Multidrug-Resistant Klebsiella variicola Coproducing IMP-4 and NDM-1 Carbapenemases
por: Wang, Bingjie, et al.
Publicado: (2022)

Emergence of a Superplasmid Coharboring Hypervirulence and Multidrug Resistance Genes in Klebsiella pneumoniae Poses New Challenges to Public Health
por: Jia, Xinmiao, et al.
Publicado: (2022)

Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae
por: Bulman, Zackery P., et al.
Publicado: (2021)

Epidemiological characteristics and risk factors of nosocomial carbapenem-resistant Enterobacteriaceae infections in children
por: Li, Zhe, et al.
Publicado: (2020)

Multidrug-Resistant Gram-Negative Bacteria and Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae from the Poultry Farm Environment
por: Veloo, Yuvaneswary, et al.
Publicado: (2022)

Limiting and controlling carbapenem-resistant Klebsiella pneumoniae
por: Saidel-Odes, Lisa, et al.
Publicado: (2013)

No Carbapenem Resistance in Pneumonia Caused by Klebsiella Species
por: Yayan, Josef, et al.
Publicado: (2015)

Epidemiological Study of Carbapenem-resistant Klebsiella Pneumoniae
por: Lin, Di, et al.
Publicado: (2018)

Evolution of Bacterial Cross-Resistance to Lytic Phages and Albicidin Antibiotic
por: Kortright, Kaitlyn E., et al.
Publicado: (2021)

Safety and Efficacy of a Phage, kpssk3, in an in vivo Model of Carbapenem-Resistant Hypermucoviscous Klebsiella pneumoniae Bacteremia
por: Shi, Yunlong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rslmghbvrvnsan85d9skefuoan