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A Nonclassical Mechanism of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus and Its Effect on Virulence

Methicillin-resistant Staphylococcus aureus (MRSA) is a group of pathogenic bacteria that are infamously resistant to β-lactam antibiotics, a property attributed to the mecA gene. Recent studies have reported that mutations associated with the promoter region of pbp4 demonstrated high levels of β-la...

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Detalles Bibliográficos
Autores principales: Satishkumar, Nidhi, Lai, Li-Yin, Mukkayyan, Nagaraja, Vogel, Bruce E., Chatterjee, Som S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769611/
https://www.ncbi.nlm.nih.gov/pubmed/36314912
http://dx.doi.org/10.1128/spectrum.02284-22