Two Different Phospholipases C, Isc1 and Pgc1, Cooperate To Regulate Mitochondrial Function

The absence of Isc1, the yeast homologue of mammalian neutral sphingomyelinase type 2, leads to severe mitochondrial dysfunction. We show that the deletion of another type C phospholipase, the phosphatidylglycerol (PG)-specific phospholipase Pgc1, rescues this defect. Phosphatidylethanolamine (PE) l...

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Detalles Bibliográficos
Autores principales: Balazova, Maria, Vesela, Petra, Babelova, Lenka, Durisova, Ivana, Kanovicova, Paulina, Zahumensky, Jakub, Malinsky, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769635/
https://www.ncbi.nlm.nih.gov/pubmed/36377885
http://dx.doi.org/10.1128/spectrum.02489-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769635/
https://www.ncbi.nlm.nih.gov/pubmed/36377885
http://dx.doi.org/10.1128/spectrum.02489-22

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