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Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids

Plasmid-mediated antimicrobial resistance is one of the major threats to public health worldwide. The mechanisms involved in the plasmid/host coadaptation are still poorly characterized, and their understanding is crucial to comprehend the genesis and evolution of multidrug-resistant bacteria. With...

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Detalles Bibliográficos
Autores principales: Ares-Arroyo, Manuel, Fernández-García, Miguel, Wedel, Emilia, Montero, Natalia, Barbas, Coral, Rey-Stolle, M. Fernanda, Garcia, Antonia, González-Zorn, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769657/
https://www.ncbi.nlm.nih.gov/pubmed/36416553
http://dx.doi.org/10.1128/msphere.00184-22