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Evolution of Virulence, Fitness, and Carbapenem Resistance Transmission in ST23 Hypervirulent Klebsiella pneumoniae with the Capsular Polysaccharide Synthesis Gene wcaJ Inserted via Insertion Sequence Elements

Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is recognized as a threat worldwide, but the mechanisms underlying its emergence remain unclear. As most CR-hvKP isolates are not hypermucoviscous, we speculated that the evolution of the capsule might result in the convergence of ca...

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Detalles Bibliográficos
Autores principales: Wang, Shuyi, Ding, Qi, Zhang, Yawei, Zhang, Anru, Wang, Qi, Wang, Ruobing, Wang, Xiaojuan, Jin, Longyang, Ma, Shuai, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769677/
https://www.ncbi.nlm.nih.gov/pubmed/36222687
http://dx.doi.org/10.1128/spectrum.02400-22