Cargando…
Evolution of Virulence, Fitness, and Carbapenem Resistance Transmission in ST23 Hypervirulent Klebsiella pneumoniae with the Capsular Polysaccharide Synthesis Gene wcaJ Inserted via Insertion Sequence Elements
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is recognized as a threat worldwide, but the mechanisms underlying its emergence remain unclear. As most CR-hvKP isolates are not hypermucoviscous, we speculated that the evolution of the capsule might result in the convergence of ca...
Autores principales: | Wang, Shuyi, Ding, Qi, Zhang, Yawei, Zhang, Anru, Wang, Qi, Wang, Ruobing, Wang, Xiaojuan, Jin, Longyang, Ma, Shuai, Wang, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769677/ https://www.ncbi.nlm.nih.gov/pubmed/36222687 http://dx.doi.org/10.1128/spectrum.02400-22 |
Ejemplares similares
-
Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae
por: Cai, Ruopeng, et al.
Publicado: (2019) -
Different regulatory mechanisms of the capsule in hypervirulent Klebsiella pneumonia: “direct” wcaJ variation vs. “indirect” rmpA regulation
por: Wang, Weiwen, et al.
Publicado: (2023) -
A Frameshift Mutation in wcaJ Associated with Phage Resistance in Klebsiella pneumoniae
por: Tan, Demeng, et al.
Publicado: (2020) -
Neutrophil extracellular traps (NETs)-mediated killing of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) are impaired in patients with diabetes mellitus
por: Jin, Longyang, et al.
Publicado: (2020) -
Emergence of Colistin Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Under the Pressure of Tigecycline
por: Zhang, Yawei, et al.
Publicado: (2021)