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Single Nucleotide Polymorphism-Based Real-Time PCR Screening Assay for Rapid Tracking of Bacterial Infection Clusters To Complement Whole-Genome Sequencing Efforts during Outbreak Investigations

Infection clusters of multidrug-resistant bacteria increase mortality and entail expensive infection control measures. Whereas whole-genome sequencing (WGS) is the current gold standard to confirm infection clusters, PCR-based assays targeting cluster-specific signatures, such as single nucleotide p...

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Detalles Bibliográficos
Autores principales: Treffon, Janina, Heppner, Bianca, Eismann, Julia, Bothe, Julia, Omengo, Birgit, Mellmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769705/
https://www.ncbi.nlm.nih.gov/pubmed/36250868
http://dx.doi.org/10.1128/spectrum.03036-22