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Single Nucleotide Polymorphism-Based Real-Time PCR Screening Assay for Rapid Tracking of Bacterial Infection Clusters To Complement Whole-Genome Sequencing Efforts during Outbreak Investigations
Infection clusters of multidrug-resistant bacteria increase mortality and entail expensive infection control measures. Whereas whole-genome sequencing (WGS) is the current gold standard to confirm infection clusters, PCR-based assays targeting cluster-specific signatures, such as single nucleotide p...
Autores principales: | Treffon, Janina, Heppner, Bianca, Eismann, Julia, Bothe, Julia, Omengo, Birgit, Mellmann, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769705/ https://www.ncbi.nlm.nih.gov/pubmed/36250868 http://dx.doi.org/10.1128/spectrum.03036-22 |
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