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Metabolic Engineering and Adaptive Evolution for Efficient Production of l-Lactic Acid in Saccharomyces cerevisiae

l-Lactic acid (LA) is a three-carbon hydroxycarboxylic acid with extensive applications in food, cosmetic, agricultural, pharmaceutical, and bioplastic industries. However, microbial LA production is limited by its intrinsic inefficiency of cellular metabolism. Here, pathway engineering was used to...

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Detalles Bibliográficos
Autores principales: Zhu, Pan, Luo, Rui, Li, Yize, Chen, Xiulai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769770/
https://www.ncbi.nlm.nih.gov/pubmed/36354322
http://dx.doi.org/10.1128/spectrum.02277-22