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Host Cell Oxidative Stress Promotes Intracellular Fluoroquinolone Persisters of Streptococcus pneumoniae

Bacterial persisters represent a small subpopulation that tolerates high antibiotic concentrations without acquiring heritable resistance, and it may be generated by environmental factors. Here, we report the first antibiotic persistence mechanism in Streptococcus pneumoniae, which is induced by oxi...

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Detalles Bibliográficos
Autores principales: Hernandez-Morfa, Mirelys, Reinoso-Vizcaíno, Nicolás M., Olivero, Nadia B., Zappia, Victoria E., Cortes, Paulo R., Jaime, Andrea, Echenique, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769771/
https://www.ncbi.nlm.nih.gov/pubmed/36445159
http://dx.doi.org/10.1128/spectrum.04364-22