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Breaching the Barrier: Genome-Wide Investigation into the Role of a Primary Amine in Promoting E. coli Outer-Membrane Passage and Growth Inhibition by Ampicillin

Gram-negative bacteria are problematic for antibiotic development due to the low permeability of their cell envelopes. To rationally design new antibiotics capable of breaching this barrier, more information is required about the specific components of the cell envelope that prevent the passage of c...

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Detalles Bibliográficos
Autores principales: Maher, Claire, Maharjan, Ram, Sullivan, Geraldine, Cain, Amy K., Hassan, Karl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769794/
https://www.ncbi.nlm.nih.gov/pubmed/36409154
http://dx.doi.org/10.1128/spectrum.03593-22