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Breaching the Barrier: Genome-Wide Investigation into the Role of a Primary Amine in Promoting E. coli Outer-Membrane Passage and Growth Inhibition by Ampicillin
Gram-negative bacteria are problematic for antibiotic development due to the low permeability of their cell envelopes. To rationally design new antibiotics capable of breaching this barrier, more information is required about the specific components of the cell envelope that prevent the passage of c...
Autores principales: | Maher, Claire, Maharjan, Ram, Sullivan, Geraldine, Cain, Amy K., Hassan, Karl A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769794/ https://www.ncbi.nlm.nih.gov/pubmed/36409154 http://dx.doi.org/10.1128/spectrum.03593-22 |
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