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Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection

Marek’s disease virus (MDV) induces immunosuppression and neoplastic disease in chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has the disadvantage of retaining the ability to induce lymphoid organ atrophy. To overcome this deficiency and produce more vaccine...

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Detalles Bibliográficos
Autores principales: Sun, Aijun, Zhao, Xuyang, Zhu, Xiaojing, Kong, Zhengjie, Liao, Yifei, Teng, Man, Yao, Yongxiu, Luo, Jun, Nair, Venugopal, Zhuang, Guoqing, Zhang, Gaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769808/
https://www.ncbi.nlm.nih.gov/pubmed/36350141
http://dx.doi.org/10.1128/spectrum.02871-22