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Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection
Marek’s disease virus (MDV) induces immunosuppression and neoplastic disease in chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has the disadvantage of retaining the ability to induce lymphoid organ atrophy. To overcome this deficiency and produce more vaccine...
Autores principales: | Sun, Aijun, Zhao, Xuyang, Zhu, Xiaojing, Kong, Zhengjie, Liao, Yifei, Teng, Man, Yao, Yongxiu, Luo, Jun, Nair, Venugopal, Zhuang, Guoqing, Zhang, Gaiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769808/ https://www.ncbi.nlm.nih.gov/pubmed/36350141 http://dx.doi.org/10.1128/spectrum.02871-22 |
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