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Identification of KPC-112 from an ST15 Klebsiella pneumoniae Strain Conferring Resistance to Ceftazidime-Avibactam

Ceftazidime-avibactam is an effective antibiotic combination of a β-lactam and a β-lactamase inhibitor against Klebsiella pneumoniae-carbapenemase (KPC)-producing Enterobacterales. Despite a relatively low resistance rate, reports of resistance to ceftazidime-avibactam mainly caused by the mutations...

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Detalles Bibliográficos
Autores principales: Shen, Siquan, Tang, Chengkang, Ding, Li, Han, Renru, Yin, Dandan, Yang, Weiwei, Guo, Yan, Hu, Fupin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769832/
https://www.ncbi.nlm.nih.gov/pubmed/36374086
http://dx.doi.org/10.1128/msphere.00487-22