Attenuated Porcine Reproductive and Respiratory Syndrome Virus Regains Its Fatal Virulence by Serial Passaging in Pigs or Porcine Alveolar Macrophages To Increase Its Adaptation to Target Cells

Porcine reproductive and respiratory syndrome (PRRS) is a globally important disease threatening the pork industry, and modified live-virus (MLV) vaccines are widely used for its prevention. However, PRRS MLV shows high potential for reversion to virulence, leading to a major concern about its safet...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Zhang, Mengsi, Cui, Xiaochun, Gao, Xiang, Sun, Weifeng, Ge, Xinna, Zhang, Yongning, Guo, Xin, Han, Jun, Zhou, Lei, Yang, Hanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769833/
https://www.ncbi.nlm.nih.gov/pubmed/36219105
http://dx.doi.org/10.1128/spectrum.03084-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769833/
https://www.ncbi.nlm.nih.gov/pubmed/36219105
http://dx.doi.org/10.1128/spectrum.03084-22

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