O-2-Alkylated Cytosine Acyclic Nucleoside Phosphonamidate Prodrugs Display Pan-Genotype Antiviral Activity against African Swine Fever Virus

African swine fever virus (ASFV) causes a highly contagious hemorrhagic disease with case fatality rates approaching 100% in domestic pigs. ASFV is responsible for substantial economic losses, but despite ongoing efforts, no vaccine or antiviral agent is currently available. Attempts to control the...

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Detalles Bibliográficos
Autores principales: Goulding, Leah V., Kiss, Eleonóra, Vrancken, Robert, Goris, Nesya, Luo, Min, Groaz, Elisabetta, Herdewijn, Piet, Dixon, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769911/
https://www.ncbi.nlm.nih.gov/pubmed/36317894
http://dx.doi.org/10.1128/msphere.00378-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769911/
https://www.ncbi.nlm.nih.gov/pubmed/36317894
http://dx.doi.org/10.1128/msphere.00378-22

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