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Enhanced Rishirilide Biosynthesis by a Rare In-Cluster Phosphopantetheinyl Transferase in Streptomyces xanthophaeus

Phosphopantetheinyl transferases (PPTases) play important roles in activating apo-acyl carrier proteins (apo-ACPs) and apo-peptidyl carrier proteins (apo-PCPs) in both primary and secondary metabolism. PPTases catalyze the posttranslational modifications of those carrier proteins by covalent attachm...

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Detalles Bibliográficos
Autores principales: Zhang, Songya, Fan, Shuai, Zhu, Jing, Zhou, Liying, Yan, Xiaohui, Yang, Zhaoyong, Si, Tong, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769936/
https://www.ncbi.nlm.nih.gov/pubmed/36326495
http://dx.doi.org/10.1128/spectrum.03247-22