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Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER Stress

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which has emerged in the last 2 years. The accessory protein ORF7a has been proposed as an immunomodulating factor that can cause dramatic inflammatory responses, but it is unk...

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Detalles Bibliográficos
Autores principales: Liu, Zhixin, Fu, Yanan, Huang, Yanping, Zeng, Feng, Rao, Jingjing, Xiao, Xiao, Sun, Xiaoguang, Jin, Hao, Li, Jian, Yang, Jing, Du, Weixing, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769937/
https://www.ncbi.nlm.nih.gov/pubmed/36326498
http://dx.doi.org/10.1128/spectrum.01509-22