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Breast tumor IGF1R regulates cell adhesion and metastasis: alignment of mouse single cell and human breast cancer transcriptomics

INTRODUCTION: The acquisition of a metastatic phenotype is the critical event that determines patient survival from breast cancer. Several receptor tyrosine kinases have functions both in promoting and inhibiting metastasis in breast tumors. Although the insulin-like growth factor 1 receptor (IGF1R)...

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Detalles Bibliográficos
Autores principales: Obr, Alison E., Bulatowicz, Joseph J., Chang, Yun-Juan, Ciliento, Virginia, Lemenze, Alexander, Maingrette, Krystopher, Shang, Quan, Gallagher, Emily J., LeRoith, Derek, Wood, Teresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769962/
https://www.ncbi.nlm.nih.gov/pubmed/36568144
http://dx.doi.org/10.3389/fonc.2022.990398