HCV Infection Increases the Expression of ACE2 Receptor, Leading to Enhanced Entry of Both HCV and SARS-CoV-2 into Hepatocytes and a Coinfection State

Recent studies suggest the enhancement of liver injury in COVID-19 patients infected with Hepatitis C virus (HCV). Hepatocytes express low levels of angiotensin-converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor, raising the possibility of HCV-SARS-CoV-2 coinfection in the liver. This work ai...

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Detalles Bibliográficos
Autores principales: Domovitz, Tom, Ayoub, Samer, Werbner, Michal, Alter, Joel, Izhaki Tavor, Lee, Yahalom-Ronen, Yfat, Tikhonov, Evgeny, Meirson, Tomer, Maman, Yaakov, Paran, Nir, Israely, Tomer, Dessau, Moshe, Gal-Tanamy, Meital
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769977/
https://www.ncbi.nlm.nih.gov/pubmed/36314945
http://dx.doi.org/10.1128/spectrum.01150-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769977/
https://www.ncbi.nlm.nih.gov/pubmed/36314945
http://dx.doi.org/10.1128/spectrum.01150-22

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