CycA-Dependent Glycine Assimilation Is Connected to Novobiocin Susceptibility in Escherichia coli

Escherichia coli serine hydroxymethyltransferase (GlyA) converts serine to glycine, and glyA mutants are auxotrophic for glycine. CycA is a transporter that mediates glycine uptake. Deleting glyA in E. coli strain W3110 led to activation of CysB, which was related to novobiocin (NOV) susceptibility....

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Detalles Bibliográficos
Autores principales: Shi, Hongmei, Zhang, Ling, Gu, Jing, Li, Jinyue, Liu, Zixiang, Deng, Jiao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769978/
https://www.ncbi.nlm.nih.gov/pubmed/36377953
http://dx.doi.org/10.1128/spectrum.02501-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769978/
https://www.ncbi.nlm.nih.gov/pubmed/36377953
http://dx.doi.org/10.1128/spectrum.02501-22

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