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Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with App(NL-G-F) Mice

Alzheimer’s Disease (AD) is characterized by the pathologic assembly of amyloid β (Aβ) peptide, which deposits into extracellular plaques, and tau, which accumulates in intraneuronal inclusions. To investigate the link between Aβ and tau pathologies, experimental models featuring both pathologies ar...

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Detalles Bibliográficos
Autores principales: Huang, Melissa, Macdonald, Jennifer, Lavenir, Isabelle, Chen, Renren, Craxton, Molly, Slavik-Smith, Elizabeth, Davies, Stephen W., Goedert, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770019/
https://www.ncbi.nlm.nih.gov/pubmed/36635241
http://dx.doi.org/10.1523/ENEURO.0247-22.2022