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FUCOIDANS ARE NOVEL SENOTHERAPEUTICS THAT ENHANCE SIRT6 AND DNA REPAIR ACTIVITY

With age, senescent cells accumulate in various tissues where they contribute to loss of tissue homeostasis, aging, and age-related diseases through their inflammatory senescence-associated secretory phenotypes (SASPs). Senotherapeutics able to selectively eliminate senescent cells, termed senolytic...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Hughes, Brian, Tombline, Gregory, Angelini, Luise, Yousefzadeh, Matt, Gorbunova, Vera, Niedernhofer, Laura, Robbins, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770113/
http://dx.doi.org/10.1093/geroni/igac059.522