Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing

Enthusiasm for using polygenic risk scores (PRSs) in clinical practice is tempered by concerns about their portability to diverse ancestry groups, thus motivating genome-wide association studies in non-European ancestry cohorts. METHODS: We conducted a genome-wide association study for coronary hear...

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Detalles Bibliográficos
Autores principales: Saad, Mohamad, El-Menyar, Ayman, Kunji, Khalid, Ullah, Ehsan, Al Suwaidi, Jassim, Kullo, Iftikhar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770120/
https://www.ncbi.nlm.nih.gov/pubmed/36252120
http://dx.doi.org/10.1161/CIRCGEN.122.003712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770120/
https://www.ncbi.nlm.nih.gov/pubmed/36252120
http://dx.doi.org/10.1161/CIRCGEN.122.003712

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