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The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis

Genome-wide association studies have discovered a link between genetic variants on human chromosome 15q26.1 and increased coronary artery disease (CAD) susceptibility; however, the underlying pathobiological mechanism is unclear. This genetic locus contains the FES (FES proto-oncogene, tyrosine kina...

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Detalles Bibliográficos
Autores principales: Karamanavi, Elisavet, McVey, David G., van der Laan, Sander W., Stanczyk, Paulina J., Morris, Gavin E., Wang, Yifan, Yang, Wei, Chan, Kenneth, Poston, Robin N., Luo, Jun, Zhou, Xinmiao, Gong, Peng, Jones, Peter D., Cao, Junjun, Kostogrys, Renata B., Webb, Tom R., Pasterkamp, Gerard, Yu, Haojie, Xiao, Qingzhong, Greer, Peter A., Stringer, Emma J., Samani, Nilesh J., Ye, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770135/
https://www.ncbi.nlm.nih.gov/pubmed/36321446
http://dx.doi.org/10.1161/CIRCRESAHA.122.321146