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Blocking MG53(S255) Phosphorylation Protects Diabetic Heart From Ischemic Injury
As an integral component of cell membrane repair machinery, MG53 (mitsugumin 53) is important for cardioprotection induced by ischemia preconditioning and postconditioning. However, it also impairs insulin signaling via its E3 ligase activity-mediated ubiquitination-dependent degradation of IR (insu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770150/ https://www.ncbi.nlm.nih.gov/pubmed/36337049 http://dx.doi.org/10.1161/CIRCRESAHA.122.321055 |