Cargando…

Blocking MG53(S255) Phosphorylation Protects Diabetic Heart From Ischemic Injury

As an integral component of cell membrane repair machinery, MG53 (mitsugumin 53) is important for cardioprotection induced by ischemia preconditioning and postconditioning. However, it also impairs insulin signaling via its E3 ligase activity-mediated ubiquitination-dependent degradation of IR (insu...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Fengxiang, Wang, Yingfan, Shan, Dan, Guo, Sile, Chen, Gengjia, Jin, Li, Zheng, Wen, Feng, Han, Zeng, Xiaohu, Zhang, Shuo, Zhang, Yan, Hu, Xinli, Xiao, Rui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770150/
https://www.ncbi.nlm.nih.gov/pubmed/36337049
http://dx.doi.org/10.1161/CIRCRESAHA.122.321055