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PACAP and acetylcholine cause distinct Ca(2+) signals and secretory responses in chromaffin cells

The adrenomedullary chromaffin cell transduces chemical messages into outputs that regulate end organ function throughout the periphery. At least two important neurotransmitters are released by innervating preganglionic neurons to stimulate exocytosis in the chromaffin cell—acetylcholine (ACh) and p...

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Detalles Bibliográficos
Autores principales: Morales, Alina, Mohan, Ramkumar, Chen, Xiaohuan, Coffman, Breanna L., Bendahmane, Mounir, Watch, Lester, West, Joshua L., Bakshi, Shreeya, Traynor, John R., Giovannucci, David R., Kammermeier, Paul J., Axelrod, Daniel, Currie, Kevin P.M., Smrcka, Alan V., Anantharam, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770323/
https://www.ncbi.nlm.nih.gov/pubmed/36538657
http://dx.doi.org/10.1085/jgp.202213180