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Assessment of mouse VEGF neutralization by ranibizumab and aflibercept

PURPOSE: To assess the interaction between ranibizumab, aflibercept, and mouse vascular endothelial growth factor (VEGF), both in vivo and in vitro. METHODS: In vivo, the effect of intravitreal injection of ranibizumab and aflibercept on oxygen induced retinopathy (OIR) and the effect of multiple in...

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Detalles Bibliográficos
Autores principales: Ichiyama, Yusuke, Matsumoto, Riko, Obata, Shumpei, Sawada, Osamu, Saishin, Yoshitsugu, Kakinoki, Masashi, Sawada, Tomoko, Ohji, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770341/
https://www.ncbi.nlm.nih.gov/pubmed/36542626
http://dx.doi.org/10.1371/journal.pone.0278951