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Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera

As a leading cause of death in children under 5 years old, secretory diarrheas including cholera are characterized by excessive intestinal fluid secretion driven by enterotoxin-induced cAMP-dependent intestinal chloride transport. This study aimed to identify fungal bioactive metabolites possessing...

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Detalles Bibliográficos
Autores principales: Noitem, Rattikarn, Pongkorpsakol, Pawin, Changsen, Chartchai, Sukpondma, Yaowapa, Tansakul, Chittreeya, Rukachaisirikul, Vatcharin, Muanprasat, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770395/
https://www.ncbi.nlm.nih.gov/pubmed/36490300
http://dx.doi.org/10.1371/journal.pntd.0010989