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Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization

Extracellular matrix (ECM) interactions regulate both the cell transcriptome and proteome, thereby determining cell fate. Traumatic heterotopic ossification (HO) is a disorder characterized by aberrant mesenchymal lineage (MLin) cell differentiation, forming bone within soft tissues of the musculosk...

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Detalles Bibliográficos
Autores principales: Pagani, Chase A., Bancroft, Alec C., Tower, Robert J., Livingston, Nicholas, Sun, Yuxiao, Hong, Jonathan Y., Kent, Robert N., Strong, Amy L., Nunez, Johanna H., Medrano, Jessica Marie R., Patel, Nicole, Nanes, Benjamin A., Dean, Kevin M., Li, Zhao, Ge, Chunxi, Baker, Brendon M., James, Aaron W., Weiss, Stephen J., Franceschi, Renny T., Levi, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770942/
https://www.ncbi.nlm.nih.gov/pubmed/36542719
http://dx.doi.org/10.1126/sciadv.abq6152