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Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel

Salivary gland acinar cells are severely depleted after radiotherapy for head and neck cancer, leading to loss of saliva and extensive oro-digestive complications. With no regenerative therapies available, organ dysfunction is irreversible. Here, using the adult murine system, we demonstrate that ra...

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Detalles Bibliográficos
Autores principales: Li, Jianlong, Sudiwala, Sonia, Berthoin, Lionel, Mohabbat, Seayar, Gaylord, Eliza A., Sinada, Hanan, Cruz Pacheco, Noel, Chang, Jiun Chiun, Jeon, Oju, Lombaert, Isabelle M.A., May, Alison J., Alsberg, Eben, Bahney, Chelsea S., Knox, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770982/
https://www.ncbi.nlm.nih.gov/pubmed/36542703
http://dx.doi.org/10.1126/sciadv.adc8753