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Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel
Salivary gland acinar cells are severely depleted after radiotherapy for head and neck cancer, leading to loss of saliva and extensive oro-digestive complications. With no regenerative therapies available, organ dysfunction is irreversible. Here, using the adult murine system, we demonstrate that ra...
Autores principales: | Li, Jianlong, Sudiwala, Sonia, Berthoin, Lionel, Mohabbat, Seayar, Gaylord, Eliza A., Sinada, Hanan, Cruz Pacheco, Noel, Chang, Jiun Chiun, Jeon, Oju, Lombaert, Isabelle M.A., May, Alison J., Alsberg, Eben, Bahney, Chelsea S., Knox, Sarah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770982/ https://www.ncbi.nlm.nih.gov/pubmed/36542703 http://dx.doi.org/10.1126/sciadv.adc8753 |
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