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Mechanisms of DNA opening revealed in AAA+ transcription complex structures

Gene transcription is carried out by RNA polymerase (RNAP) and requires the conversion of the initial closed promoter complex, where DNA is double stranded, to a transcription-competent open promoter complex, where DNA is opened up. In bacteria, RNAP relies on σ factors for its promoter specificitie...

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Detalles Bibliográficos
Autores principales: Ye, Fuzhou, Gao, Forson, Liu, Xiaojiao, Buck, Martin, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770992/
https://www.ncbi.nlm.nih.gov/pubmed/36542713
http://dx.doi.org/10.1126/sciadv.add3479