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Exosomal miR-485-3p derived from pancreatic ductal epithelial cells inhibits pancreatic cancer metastasis through targeting PAK1

BACKGROUND: Cell competition is an important feature in pancreatic cancer (PC) progression, but the underlying mechanism remains elusive. This study aims to explore the role of exosomes derived from normal pancreatic ductal epithelial cells involved in PC progression. METHODS: PC cells and pancreati...

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Detalles Bibliográficos
Autores principales: Li, Mingzhe, Zhou, Jiaxin, Zhang, Zhengkui, Li, Jisong, Wang, Feng, Ma, Ling, Tian, Xiaodong, Mao, Zebin, Yang, Yinmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771326/
https://www.ncbi.nlm.nih.gov/pubmed/36535010
http://dx.doi.org/10.1097/CM9.0000000000002154