Multivalency, autoinhibition, and protein disorder in the regulation of interactions of dynein intermediate chain with dynactin and the nuclear distribution protein

As the only major retrograde transporter along microtubules, cytoplasmic dynein plays crucial roles in the intracellular transport of organelles and other cargoes. Central to the function of this motor protein complex is dynein intermediate chain (IC), which binds the three dimeric dynein light chai...

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Detalles Bibliográficos
Autores principales: Jara, Kayla A, Loening, Nikolaus M, Reardon, Patrick N, Yu, Zhen, Woonnimani, Prajna, Brooks, Coban, Vesely, Cat H, Barbar, Elisar J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771362/
https://www.ncbi.nlm.nih.gov/pubmed/36416224
http://dx.doi.org/10.7554/eLife.80217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771362/
https://www.ncbi.nlm.nih.gov/pubmed/36416224
http://dx.doi.org/10.7554/eLife.80217

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