DNA damage independent inhibition of NF-κB transcription by anthracyclines

Anthracyclines are among the most used and effective anticancer drugs. Their activity has been attributed to DNA double-strand breaks resulting from topoisomerase II poisoning and to eviction of histones from select sites in the genome. Here, we show that the extensively used anthracyclines Doxorubi...

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Detalles Bibliográficos
Autores principales: Chora, Angelo Ferreira, Pedroso, Dora, Kyriakou, Eleni, Pejanovic, Nadja, Colaço, Henrique, Gozzelino, Raffaella, Barros, André, Willmann, Katharina, Velho, Tiago, Moita, Catarina F, Santos, Isa, Pereira, Pedro, Carvalho, Silvia, Martins, Filipa Batalha, Ferreira, João A, de Almeida, Sérgio Fernandes, Benes, Vladimir, Anrather, Josef, Weis, Sebastian, Soares, Miguel P, Geerlof, Arie, Neefjes, Jacques, Sattler, Michael, Messias, Ana C, Neves-Costa, Ana, Moita, Luis Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771368/
https://www.ncbi.nlm.nih.gov/pubmed/36476511
http://dx.doi.org/10.7554/eLife.77443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771368/
https://www.ncbi.nlm.nih.gov/pubmed/36476511
http://dx.doi.org/10.7554/eLife.77443

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