Cargando…

Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors

We aimed to elucidate the evolutionary trajectories of gallbladder adenocarcinoma (GBAC) using multi-regional and longitudinal tumor samples. Using whole-exome sequencing data, we constructed phylogenetic trees in each patient and analyzed mutational signatures. A total of 11 patients including 2 ra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Minsu, Na, Hee Young, Ahn, Soomin, Kim, Ji-Won, Lee, Sejoon, Ahn, Soyeon, Lee, Ju Hyun, Youk, Jeonghwan, Kim, Haesook T, Kim, Kui-Jin, Suh, Koung Jin, Lee, Jun Suh, Kim, Se Hyun, Kim, Jin Won, Kim, Yu Jung, Lee, Keun-Wook, Yoon, Yoo-Seok, Kim, Jee Hyun, Chung, Jin-Haeng, Han, Ho-Seong, Lee, Jong Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771369/ https://www.ncbi.nlm.nih.gov/pubmed/36476508 http://dx.doi.org/10.7554/eLife.78636

Ejemplares similares

A Prognostic Model to Facilitate Palliative Care Referral in Oncology Outpatients
por: Kim, Yu Jung, et al.
Publicado: (2022)

Performance of clinician prediction of survival in oncology outpatients with advanced cancer
por: Kim, Yu Jung, et al.
Publicado: (2022)

Clinical Application of Next-Generation Sequencing in Patients With Breast Cancer: Real-World Data
por: Suh, Koung Jin, et al.
Publicado: (2022)

Clinical characteristics and disease course of splanchnic vein thrombosis in gastrointestinal cancers: A prospective cohort study
por: Kang, Minsu, et al.
Publicado: (2022)

Effect of Platinum-Based Chemotherapy on PD-L1 Expression on Tumor Cells in Non-small Cell Lung Cancer
por: Shin, Junghoon, et al.
Publicado: (2019)

PI3K p110α Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells
por: Lee, Hyun Jung, et al.
Publicado: (2020)

Afatinib Overcomes Pemetrexed-Acquired Resistance in Non-Small Cell Lung Cancer Cells Harboring an EML4-ALK Rearrangement
por: Kwon, Ji-Hyun, et al.
Publicado: (2019)

R-MPV followed by high-dose chemotherapy with thiotepa-based and autologous stem cell transplantation for newly diagnosed primary central nervous system lymphoma: a single-center experience
por: Lee, Ji Yun, et al.
Publicado: (2021)

A population-based outcomes study of patients with metastatic gastric cancer receiving second-line chemotherapy: A nationwide health insurance database study
por: Choi, In Sil, et al.
Publicado: (2018)

BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression
por: Kim, Se Hyun, et al.
Publicado: (2018)

Clinical validity of oncogenic driver genes detected from circulating tumor DNA in the blood of lung cancer patients
por: Kim, Sheehyun, et al.
Publicado: (2023)

PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer
por: Kim, Kui-Jin, et al.
Publicado: (2020)

Treatment patterns and outcomes in patients with metastatic gastric cancer receiving third-line chemotherapy: A population-based outcomes study
por: Choi, In Sil, et al.
Publicado: (2018)

The effect of metformin or dipeptidyl peptidase 4 inhibitors on clinical outcomes in metastatic non‐small cell lung cancer treated with immune checkpoint inhibitors
por: Yang, Jieun, et al.
Publicado: (2022)

Acute pulmonary thromboembolism caused by factor V Leiden mutation in South Korea: A case report
por: Choe, Hun Jee, et al.
Publicado: (2019)

Prevalence and Risk Factors for Iron Deficiency Anemia in the Korean Population: Results of the Fifth Korea National Health and Nutrition Examination Survey
por: Lee, Jeong-Ok, et al.
Publicado: (2014)

Identification of a potentially avoidable cardiopulmonary resuscitation in hematology and oncology wards
por: Choi, Yeonjoo, et al.
Publicado: (2019)

Tumor LAG‐3 and NY‐ESO‐1 expression predict durable clinical benefits of immune checkpoint inhibitors in advanced non‐small cell lung cancer
por: Jung, Eun Hee, et al.
Publicado: (2021)

The relationship between nuclear factor (NF)-κB family gene expression and prognosis in triple-negative breast cancer (TNBC) patients receiving adjuvant doxorubicin treatment
por: Kim, Ji-Yeon, et al.
Publicado: (2016)

Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer
por: Kim, Sang-A, et al.
Publicado: (2021)

Korean translation of the CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials
por: Lee, Jun Suh, et al.
Publicado: (2014)

Centromere 17 copy number gain reflects chromosomal instability in breast cancer
por: Lee, Kyoungyul, et al.
Publicado: (2019)

Programmed death-ligand 1 expression level as a predictor of EGFR tyrosine kinase inhibitor efficacy in lung adenocarcinoma
por: Kang, Minsu, et al.
Publicado: (2021)

Reference Values for the Revised Anti-Müllerian Hormone Generation II Assay: Infertile Population-based Study
por: Lee, Joong Yeup, et al.
Publicado: (2017)

Comparison of the Predictive Power of a Combination versus Individual Biomarker Testing in Non–Small Cell Lung Cancer Patients Treated with Immune Checkpoint Inhibitors
por: Kim, Hyojin, et al.
Publicado: (2022)

Development of a Multi-Layer Skin Substitute Using Human Hair Keratinic Extract-Based Hybrid 3D Printing
por: Choi, Won Seok, et al.
Publicado: (2021)

EGFR or HER2 inhibition modulates the tumor microenvironment by suppression of PD-L1 and cytokines release
por: Suh, Koung Jin, et al.
Publicado: (2017)

Expression of Nicotinic Acetylcholine Receptor α4 and β2 Subunits on Direction-Selective Retinal Ganglion Cells in the Rabbit
por: Lee, Jun-Seok, et al.
Publicado: (2017)

Correlation between tumor infiltrating immune cells and peripheral regulatory T cell determined using methylation analyses and its prognostic significance in resected gastric cancer
por: Suh, Koung Jin, et al.
Publicado: (2021)

EUS-guided fine-needle biopsy of gallbladder polypoid lesions
por: Kang, Sung Hoon, et al.
Publicado: (2020)

Innovation of EUS-guided transmural gallbladder drainage using a novel self-expanding metal stent
por: Huh, Gunn, et al.
Publicado: (2020)

Breast Cancer Epidemiology of the Working-Age Female Population Reveals Significant Implications for the South Korean Economy
por: Park, Jeong Hyun, et al.
Publicado: (2018)

Dissecting single-cell genomes through the clonal organoid technique
por: Youk, Jeonghwan, et al.
Publicado: (2021)

Prognostic Significance of Tumor Location in T2 Gallbladder Cancer: A Systematic Review and Meta-Analysis
por: Kang, Hyun, et al.
Publicado: (2021)

Acquired factor VIII deficiency after consuming the dried gallbladder of a cobra, Naja naja
por: Kim, Hyun Ju, et al.
Publicado: (2010)

Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells
por: Lee, Chan-Hee, et al.
Publicado: (2010)

Cessation of gonadotropin-releasing hormone antagonist on triggering day in flexible multiple-dose protocol: A randomized controlled study
por: Chang, Hye Jin, et al.
Publicado: (2013)

Platelet to lymphocyte ratio (PLR) retains independent prognostic significance in advanced stage marginal zone lymphoma patients treated with rituximab, cyclophosphamide, vincristine, and prednisone combination chemotherapy (R-CVP): Consortium for Improving Survival of Lymphoma trial
por: Seo, Jeongkuk, et al.
Publicado: (2017)

Lung Cancer in Homeless People: Clinical Outcomes and Cost Analysis in a Single Institute
por: Suh, Koung Jin, et al.
Publicado: (2016)

Immune recurrence score using 7 immunoregulatory protein expressions can predict recurrence in stage I–III breast cancer patients
por: Lee, Dae-Won, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_699d6duroh46hfb73fqqaecqtc