Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts

The myocardium is a mechanically active tissue typified by anisotropy of the resident cells [cardiomyocytes (CMs) and cardiac fibroblasts (cFBs)] and the extracellular matrix (ECM). Upon ischemic injury, the anisotropic tissue is replaced by disorganized scar tissue, resulting in loss of coordinated...

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Detalles Bibliográficos
Autores principales: Mostert, Dylan, Groenen, Bart, Klouda, Leda, Passier, Robert, Goumans, Marie-Jose, Kurniawan, Nicholas A., Bouten, Carlijn V. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771596/
https://www.ncbi.nlm.nih.gov/pubmed/36567768
http://dx.doi.org/10.1063/5.0108914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771596/
https://www.ncbi.nlm.nih.gov/pubmed/36567768
http://dx.doi.org/10.1063/5.0108914

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