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Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts
The myocardium is a mechanically active tissue typified by anisotropy of the resident cells [cardiomyocytes (CMs) and cardiac fibroblasts (cFBs)] and the extracellular matrix (ECM). Upon ischemic injury, the anisotropic tissue is replaced by disorganized scar tissue, resulting in loss of coordinated...
Autores principales: | Mostert, Dylan, Groenen, Bart, Klouda, Leda, Passier, Robert, Goumans, Marie-Jose, Kurniawan, Nicholas A., Bouten, Carlijn V. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771596/ https://www.ncbi.nlm.nih.gov/pubmed/36567768 http://dx.doi.org/10.1063/5.0108914 |
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