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Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins
Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, screening using antigens with subphysiological conformation in a nonmembrane environment signifi...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771723/ https://www.ncbi.nlm.nih.gov/pubmed/36570769 http://dx.doi.org/10.1016/j.isci.2022.105736 |